{
  "version": 1,
  "planning": {
    "type": "Normal approximation for two equal independent groups; known equal variance",
    "alpha": 0.05,
    "power": 0.8,
    "z_alpha_two_sided": 1.959963984540054,
    "z_power": 0.8416212335729143,
    "formula": "n_per_group = ceil(2 * (z_alpha + z_power)^2 * (CV_percent / effect_percent)^2)",
    "limitations": [
      "Variance must be justified",
      "Small samples and estimated variance require a tailored analysis",
      "Technical readings do not count as independent preparations",
      "Blocking, batch effects and multiple comparisons change the design"
    ],
    "source": "https://www.itl.nist.gov/div898/handbook/prc/section2/prc222.htm"
  },
  "supply": {
    "type": "Hypothetical ingredient-supply scenario, not a Bio forecast",
    "currency": "GBP",
    "kg": "accounts * SKUs * annual_units_per_SKU * (finished_mass_g / 1000) * (inclusion_percent / 100)",
    "net_price": "gross_price_GBP_per_kg * net_realisation_percent / 100",
    "variable_contribution": "kg * (net_price - variable_cost_per_saleable_kg)",
    "remaining": "variable_contribution - entered_annual_fixed_allowance",
    "break_even": "fixed_allowance / positive_unit_contribution; otherwise no finite break-even",
    "exclusions": [
      "Taxes",
      "Time and working capital",
      "Unentered costs",
      "Development and capital expenditure",
      "Licensing and paid-development revenues"
    ]
  },
  "boundary": "No Bio experimental data, committed customers, validated inclusion level, verified cost or investment returns are claimed."
}